Xeroderma Pigmentosum or XP is a very rare, heritable
disorder. A genetic defect in ultraviolet radiation induced DNA repair
mechanisms. Distinguishing features; increase sensitivity to UV radiation,
especially sun light.
Early intervention and diagnosis can delay the onset of it’s many complications.
and or can lead to death. It appears typically by 1 – 2 years of
age, with the detection of severe sunburn with just the very minimal exposure
to sunlight, and freckles – like spots on exposed areas, later symptoms
includes; premature aging, cancer of the skin, eye problems and neurologic
abnormalities can develop.
Xeroderma pigmentosum is categorized in different groups according
to the capacity of the body to repair DNA.
Sun – burns easily, developing blisters with just minimal sun exposure
Dwarfism ( hypergonadism )
Failure of muscular coordination
Can be life threatening
Early detection and interventions
Management of this disorder
Gene therapy for DNA repair
Seek medical treatment promptly if you suspect your child to have
sensitivity to any UV source.