Squamous Cell Carcinoma

Squamous cell carcinoma: The skin cancer is an invasive tumor with

potential. It may be caused by overexposure to ultraviolet rays,
X – ray therapy,

chronic skin irritation and inflammation, ingestion of herbicides containing
arsenic, and

exposure to local carcinogens such as tar, and oil. Risk factors
include being white

male, and over age 60. Those who work outdoors and are expose to
the sun, those

who have a pre malignant lesion. Squamous cell carcinoma commonly
develops on

sun damaged areas of the skin.


A nodule growing on a firm indurated base, there may be some ulceration
at the lesion

site ( if carcinoma develops in normal skin )

A pre malignant, preexisting lesion may be inflamed and indurated.
Metastasis to

regional lymph nodes may cause pain, malaise, fatigue, weakness, and anorexia

Diagnostic test – Excisional biopsy of the lesion confirms the diagnosis


Depending on the lesion, treatment may consist of wide surgical excision

electrodesiccation and curettage.

Radiation therapy ( usually used for older or debilitated patients)

Moh’s surgery also may be indicated.

* Regular follow up with your doctor is important

Call your doctor if you have any of the above symptoms.


Cancer treatments seek to destroy malignant cells while sparing normal
ones, to

reduce pain, and to induce cure or remission. A single primary treatment
or a

combination of treatments may be used. These treatments can provide
local and

systemic therapy and offer doctors the advantage of attacking cancer cells

several mechanisms. They include:

* Chemotherapy – which interrupts malignant cells life cycles, inhibiting
or destroying

their ability to divide

* Radiation – which also inhibits cell division by impairing DNA synthesis
and causing

cell membrane lysis. Radiation can be used as a primary treatment
or as an adjunctive

procedure intended to kill cancer cells that may have survived other treatments.

* Biotherapy ( immunotherapy ), which employs biological response modifiers

act on malignant cells by inhibiting division and by enhancing the body’s

responses to such cells.

* Bone marrow transplantation, which is used to replace or replenish the

marrow of patients with leukemia or multiple myeloma

* Surgery, which removes tumors or reduces their size. Surgery enables

treatments because there are fewer malignant cells to combat.

* Several new cancer treatments are emerging. surgical treatments
using lasers and

intraoperative radiation can effectively remove tumors or reduce their
size at the time

of initial surgery and staging. Hyperthermia – the use of heat to
destroy cancer cells is

being investigated as a single modality and in combination with radiation